产品名称

Dnmt3b Antibody Antibody

产品货号

AF300068

基因名称

Dnmt3b

蛋白名称

Dnmt3b

其他名称

Dnmt3b; DNA methyltransferase HsaIIIB; DNMT3B;

SwissPro

Human:Q9UBC3    

宿主种属

Rabbit

应用范围

WB ICC/IF

稀释比例

WB 1:500~1:2000 ICC/IF 1:50~1:200

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Dnmt3b

特异性

Dnmt3b Antibody Antibody detects endogenous levels of total Dnmt3b

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

96kDa

产品概述

Required for genome wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing (By similarity).