产品名称 | RNF20 Antibody |
产品货号 | AF300071 |
基因名称 | RNF20 |
蛋白名称 | RNF20 |
其他名称 | BRE1-A; hBRE1; RING finger protein 20; E3 ubiquitin-protein ligase BRE1A; RNF20; |
SwissPro | Human:Q5VTR2     |
宿主种属 | Rabbit |
应用范围 | WB ICC/IF IP FC |
稀释比例 | WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50 FC 1:50 |
反应种属 | Human Mouse |
克隆性 | Monoclonal |
免疫原 | A synthesized peptide derived from human RNF20 |
特异性 | RNF20 Antibody detects endogenous levels of total RNF20 |
同种型 | Rabbit IgG |
保存液 | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
纯化方式 | Affinity-chromatography |
保存条件 | -20°C/1 year |
背景资料 | 114kDa |
产品概述 | RNF20 is an E3 ubiquitin ligase protein that mediates monoubiquitination of histone H2B and the methylation of histone H3. It forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBE2E1/UBCH6. It thereby plays a central role in histone code and gene regulation. It is required for transcriptional activation of Hox genes. |