产品名称

Caveolin-1 Antibody

产品货号

AF300083

基因名称

Caveolin-1

蛋白名称

Caveolin-1

其他名称

BSCL3; CGL3; caveolin 1, caveolae protein, 22kDa; Caveolin-1; VIP21; CAV; CAV1.

SwissPro

Human:Q03135    

宿主种属

Rabbit

应用范围

WB IHC ICC/IF

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Caveolin-1

特异性

Caveolin-1 Antibody detects endogenous levels of total Caveolin-1

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

25kDa

产品概述

Caveolin-1 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pa