产品名称

Cleaved PARP Antibody

产品货号

AF300097

基因名称

Cleaved PARP

蛋白名称

Cleaved PARP

其他名称

PPOL; ADPRT; ADPRT1; pADPRT-1; PARP; PARP-1;

SwissPro

Human:P09874    

宿主种属

Rabbit

应用范围

WB IHC

稀释比例

WB 1:500~1:2000 IHC 1:50~1:100

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Cleaved PARP

特异性

This antibody is specific for the p25 cleaved form of human PARP.

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

25kDa

产品概述

Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.