产品名称

ER alpha Antibody

产品货号

AF300103

基因名称

ER alpha

蛋白名称

ER alpha

其他名称

ER; ESR; ESR1; Era; ESRA; NR3A1;

SwissPro

Human:P03372    

宿主种属

Rabbit

应用范围

WB IHC ICC/IF ChIP FC

稀释比例

WB 1:500~1:2000 IHC 1:50~1:100 ICC/IF 1:50~1:100 ChIP 5 ?g/30 ?g FC 1:30

反应种属

Human Mouse Rat Dog

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human ER alpha

特异性

ER alpha Antibody detects endogenous levels of total ER alpha

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

60kDa

产品概述

ER (estrogen receptor 1) a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ER activity. ER is phosphorylated on multiple sites.