产品名称

Phospho-Erk1 (T202/Y204) + Erk2 (T185/Y187) Antibody

产品货号

AF300106

基因名称

Phospho-Erk1 (T202/Y204) + Erk2 (T185/Y187)

蛋白名称

Phospho-Erk1 (T202/Y204) + Erk2 (T185/Y187)

其他名称

MAPK3; MK03; MNK1; p44-ERK1; P44-ER; ERK-1; ERK1; ERT2; kinase ERK1; MAP kinase 1; MAPK 1;

SwissPro

Human:P27361    

宿主种属

Rabbit

应用范围

WB IHC ICC/IF FC

稀释比例

WB 1:500~1:2000 IHC 1:50~1:100 ICC/IF 1:50~1:100 FC 1:40

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Phospho-Erk1 (T202/Y204) + Erk2 (T185/Y187)

特异性

Phospho-Erk1 (T202/Y204) + Erk2 (T185/Y187) Antibody detects endogenous levels of total Phospho-Erk1 (T202/Y204) + Erk2 (T185/Y187)

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

42kDa/44kDa

产品概述

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, c