产品名称

Mutant p53 Antibody

产品货号

AF300109

基因名称

Mutant p53

蛋白名称

Mutant p53

其他名称

Antigen NY-CO-13; TP53; Tumor suppressor p53; Cellular tumor antigen p53; Phosphoprotein p53;

SwissPro

Human:P04637    

宿主种属

Rabbit

应用范围

WB ICC/IF IP FC

稀释比例

WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Mutant p53

特异性

Mutant p53 Antibody detects endogenous levels of total Mutant p53

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

53kDa

产品概述

Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.