产品名称

Phospho-PP2A alpha (Y307) Antibody

产品货号

AF300119

基因名称

Phospho-PP2A alpha (Y307)

蛋白名称

Phospho-PP2A alpha (Y307)

其他名称

eplication protein C; PP2A-alpha; Replication protein C; RP-C; PPP2CA; MGC786

SwissPro

Human:P67775    

宿主种属

Rabbit

应用范围

WB IHC ICC/IF IP

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Phospho-PP2A alpha (Y307)

特异性

Phospho-PP2A alpha (Y307) Antibody detects endogenous levels of total Phospho-PP2A alpha (Y307)

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

35kDa

产品概述

PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.