产品名称

HMGB1 Antibody

产品货号

AF300121

基因名称

HMGB1

蛋白名称

HMGB1

其他名称

HMGB1; HMG3; HMG1; SBP 1; Amphoterin;

SwissPro

Human:P09429    

宿主种属

Rabbit

应用范围

WB IHC ICC/IF FC

稀释比例

WB 1:1000~1:2000 IHC 1:50~1:100 ICC/IF 1:50~1:100 FC 1:30

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human HMGB1

特异性

HMGB1 Antibody detects endogenous levels of total HMGB1

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

25kDa

产品概述

High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFκB family, ATF-2 and c-Jun to activate transcription.