产品名称

HDAC2 Antibody

产品货号

AF300123

基因名称

HDAC2

蛋白名称

HDAC2

其他名称

HDAC2; HD2; Histone deacetylase 2; RPD3; YAF1; YY1 associated factor 1;

SwissPro

Human:Q92769    

宿主种属

Rabbit

应用范围

WB IHC ICC/IF IP FC

稀释比例

WB 1:1000~1:2000 IHC 1:50~1:100 ICC/IF 1:50~1:100 IP 1:30 FC 1:50

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human HDAC2

特异性

HDAC2 Antibody detects endogenous levels of total HDAC2

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

55kDa

产品概述

In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DN