产品名称

PTBP2 Antibody

产品货号

AF300135

基因名称

PTBP2

蛋白名称

PTBP2

其他名称

brPTB; MIBP; nPTB; Polypyrimidine tract binding protein 2; PTB like protein; PTBP 2Ptbp2; Splicing regulator;

SwissPro

Human:Q9UKA9    

宿主种属

Rabbit

应用范围

WB IHC ICC/IF

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human PTBP2

特异性

PTBP2 Antibody detects endogenous levels of total PTBP2

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

57kDa

产品概述

RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA.