产品名称 | SATB1 Antibody |
产品货号 | AF300139 |
基因名称 | SATB1 |
蛋白名称 | SATB1 |
其他名称 | DNA binding protein SATB1; DNA-binding protein SATB1; SATB homeobox 1; |
SwissPro | Human:Q01826     |
宿主种属 | Rabbit |
应用范围 | WB IHC ICC/IF IP FC |
稀释比例 | WB 1:500~1:3000 IHC 1:50~1:200 ICC/IF 1:100~1:500 IP 1:50~1:100 FC 1:200~1:500 |
反应种属 | Human Mouse Rat |
克隆性 | Monoclonal |
免疫原 | A synthesized peptide derived from human SATB1 |
特异性 | SATB1 Antibody detects endogenous levels of total SATB1 |
同种型 | Rabbit IgG |
保存液 | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
纯化方式 | Affinity-chromatography |
保存条件 | -20°C/1 year |
背景资料 | 100kDa |
产品概述 | SATB1 is a crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma (By similarity). Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status- |