产品名称

HIF-2 alpha Antibody

产品货号

AF300154

基因名称

HIF-2 alpha

蛋白名称

HIF-2 alpha

其他名称

bHLHe73;ECYT4;EPAS 1;EPAS1;HIF2A;HLF;MOP 2;PASD2

SwissPro

Human:Q99814    

宿主种属

Rabbit

应用范围

WB ICC/IF FC

稀释比例

WB 1:500~1:2000 ICC/IF 1:50~1:200 FC 1:50

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human HIF-2 alpha

特异性

HIF-2-alpha Antibody detects endogenous levels of total HIF-2-alpha

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

96kDa

产品概述

Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier.