产品名称

Phospho-ATM (S1981) Antibody

产品货号

AF300165

基因名称

Phospho-ATM (S1981)

蛋白名称

Phospho-ATM (S1981)

其他名称

kinase ATM; Serine-protein kinase ATM

SwissPro

Human:Q13315    

宿主种属

Rabbit

应用范围

WB IHC ICC/IF IP

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Phospho-ATM (S1981)

特异性

Phospho-ATM (S1981) Antibody detects endogenous levels of total Phospho-ATM (S1981)

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

370kDa

产品概述

The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that