产品名称

Alpha Synuclein Antibody

产品货号

AF300182

基因名称

Alpha Synuclein

蛋白名称

Alpha Synuclein

其他名称

Alpha-synuclein; NACP; non A-beta component of AD amyloid; Non-A beta component of AD amyloid; PARK1; PARK4; PD1; SNCA;

SwissPro

Human:P37840    

宿主种属

Rabbit

应用范围

WB IHC ICC/IF IP FC

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Alpha Synuclein

特异性

Alpha Synuclein Antibody detects endogenous levels of total Alpha Synuclein

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

20kDa

产品概述

May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. Genetic alterations of SNCA resulting in aberrant polymerization into fibrils, are associated with several neurodegenerative diseases (synucleinopathies).