产品名称 | Phospho-Smad3 (S423 + S425) Antibody |
产品货号 | AF300192 |
基因名称 | Phospho-Smad3 (S423 + S425) |
蛋白名称 | Phospho-Smad3 (S423 + S425) |
其他名称 | JV15-2, MAD-3, MADH3, Mad3, Mothers against DPP homolog 3, Mothers against decapentaplegic homolog 3, SMAD 3, Smad 3 |
SwissPro | Human:P84022     |
宿主种属 | Rabbit |
应用范围 | WB IHC ICC/IF |
稀释比例 | WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 |
反应种属 | Human Mouse |
克隆性 | Monoclonal |
免疫原 | A synthesized peptide derived from human Phospho-Smad3 (S423 + S425) |
特异性 | Phospho-Smad3 (S423 + S425) Antibody detects endogenous levels of total Phospho-Smad3 (S423 + S425) |
同种型 | Rabbit IgG |
保存液 | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
纯化方式 | Affinity-chromatography |
保存条件 | -20°C/1 year |
背景资料 | 55kDa |
产品概述 | Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. |