产品名称

NAK/TBK1 (N-term) Antibody

产品货号

AF300197

基因名称

NAK/TBK1 (N-term)

蛋白名称

NAK/TBK1 (N-term)

其他名称

NAK; T2K; NF-kappa-B-activating kinase; TANK-binding kinase 1; Serine/threonine-protein kinase TBK1; T2K; TANK binding kinase 1;

SwissPro

Human:Q9UHD2    

宿主种属

Rabbit

应用范围

WB IHC ICC/IF

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human NAK/TBK1 (N-term)

特异性

NAK/TBK1 (N-term) Antibody detects endogenous levels of total NAK/TBK1 (N-term)

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

84kDa

产品概述

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex.