产品名称

PMEL17 / GP100 Antibody

产品货号

AF300200

基因名称

PMEL17 / GP100

蛋白名称

PMEL17 / GP100

其他名称

PMEL; ME20-M; Premelanosome protein; Silver locus protein homolog; PMEL17; SILV;

SwissPro

Human:P40967    

宿主种属

Rabbit

应用范围

WB IHC

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human PMEL17 / GP100

特异性

PMEL17 / GP100 Antibody detects endogenous levels of total PMEL17 / GP100

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

100kDa

产品概述

Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.