产品名称

Vinculin Antibody

产品货号

AF300210

基因名称

Vinculin

蛋白名称

Vinculin

其他名称

Vinculin;VCL;Metavinculin; MV;

SwissPro

Human:P18206    

宿主种属

Rabbit

应用范围

WB ICC/IF IP

稀释比例

WB 1:10000~1:20000 ICC/IF 1:50~1:200 IP 1:50

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Vinculin

特异性

Vinculin Antibody detects endogenous levels of total Vinculin

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

125kDa

产品概述

Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development. Three structural vinculin domains include an amino-terminal head, a short, flexible proline-rich region and a carboxy-terminal tail. In the inactive state, the head and tail domains of vinculin interact to form a closed confirmation. The open and active form of vinculin translocates to focal adhesions where it is thought to be involved in anchoring F-actin to the membra