产品名称

GRP78 BiP Antibody

产品货号

AF300212

基因名称

GRP78 BiP

蛋白名称

GRP78 BiP

其他名称

GRP-78; GRP78; BIP; MIF2; HSPA5

SwissPro

Human:P11021    

宿主种属

Rabbit

应用范围

WB IHC

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human GRP78 BiP

特异性

GRP78 BiP Antibody detects endogenous levels of total GRP78 BiP

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

78kDa

产品概述

When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) (PubMed 8020977) pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER).