产品名称

MEK1/2 Antibody

产品货号

AF300214

基因名称

MEK1/2

蛋白名称

MEK1/2

其他名称

ERK activator kinase 1, MAP kinase kinase 1, MAP2K1, MAPK/ERK kinase 1, MAPKK 1, MAPKK1, MEK1, MP2K1, PRKMK1, kinase MEK1

SwissPro

Human:Q02750/P36507    

宿主种属

Rabbit

应用范围

WB IHC ICC/IF IP

稀释比例

WB 1:5000~1:10000 IHC 1:100~1:500 ICC/IF 1:50~1:100 IP 1:50~1:100

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human MEK1/2

特异性

MEK1/2 Antibody detects endogenous levels of total MEK1/2

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

44kDa

产品概述

Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2.