产品名称

TRAM2 Antibody

产品货号

AF300232

基因名称

TRAM2

蛋白名称

TRAM2

其他名称

KIAA0057;TRAM like protein;Tram2;Translocating chain associating membrane protein 2;Translocation associated membrane protein 2

SwissPro

Human:Q15035    

宿主种属

Rabbit

应用范围

WB

稀释比例

WB 1:500~1:2000

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human TRAM2

特异性

TRAM2 Antibody detects endogenous levels of total TRAM2

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

43kDa

产品概述

TRAM2 is necessary for collagen type I synthesis. May couple the activity of the ER Ca2+ pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca2+ concentration at the site of collagen synthesis, and a high Ca2+ concentration may be necessary for the function of molecular chaperones involved in collagen folding.