产品名称

BMP4 Antibody

产品货号

AF300235

基因名称

BMP4

蛋白名称

BMP4

其他名称

BMP-2B; BMP-4; BMP2B; BMP2B1; bone morphogenetic protein 4; DVR4; ZYME

SwissPro

Human:P12644    

宿主种属

Rabbit

应用范围

WB IHC ICC/IF IP FC

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human BMP4

特异性

BMP4 Antibody detects endogenous levels of total BMP4

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

47kDa

产品概述

Bone morphogenetic proteins (BMPs) were first identified as molecules that can induce ectopic bone and cartilage formation. BMPs belongs to the TGF-β superfamily, playing many diverse functions during development. BMPs are synthesized as precursor proteins and then processed by cleavage to release the c-terminal mature BMP. BMPs initiate signaling by binding to a receptor complex containing type I and type II serine/threonine receptor kinases that then phosphorylate Smad (mainly Smad1, 5 and 8),