产品名称

ATM Antibody

产品货号

AF300250

基因名称

ATM

蛋白名称

ATM

其他名称

A-T, mutated; Ataxia telangiectasia mutated; Ataxia telangiectasia mutated homolog; EC 2.7.11.1; kinase ATM; Serine-protein kinase ATM

SwissPro

Human:Q13315    

宿主种属

Rabbit

应用范围

WB IHC ICC/IF FC

稀释比例

WB 1:500~1:2000 IHC 1:50~1:100 ICC/IF 1:50~1:200 FC 1:50

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human ATM

特异性

ATM Antibody detects endogenous levels of total ATM

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

350kDa

产品概述

ATM encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1.