产品名称

Raf1 Antibody

产品货号

AF300267

基因名称

Raf1

蛋白名称

Raf1

其他名称

C-RAF, C-Raf, CRAF, EC 2.7.11.1, Protein kinase raf 1, RAF1, Raf proto-oncogene serine/threonine-protein kinase, Raf-1, kinase Raf1

SwissPro

Human:P04049    

宿主种属

Rabbit

应用范围

WB IHC ICC/IF

稀释比例

WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Raf1

特异性

Raf1 Antibody detects endogenous levels of total Raf1

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

74kDa

产品概述

Raf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2.