产品名称

Chk2 Rabbit mab

产品货号

AFRM9308

基因名称

CHEK2

蛋白名称

Serine/threonine-protein kinase Chk2

其他名称

CHEK2;CDS1;CHK2;RAD53;Serine/threonine-protein kinase Chk2;CHK2 checkpoint homolog;Cds1 homolog;Hucds1;hCds1;Checkpoint kinase 2

Gene ID

Human:11200    

SwissPro

Human:O96017    

宿主种属

Rabbit

应用范围

WB;IHC;IF;IP;ELISA

稀释比例

IHC 1:1000-1:4000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

反应种属

Human; Mouse;

克隆性

Monoclonal

克隆号

AFKL9308

特异性

endogenous

同种型

Rabbit IgG

保存液

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化方式

Protein A

保存条件

-20°C/1 year

背景资料

61kD

产品概述

In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the encoded protein is known to inhibit CDC25C phosp