产品名称

Oct-4 Rabbit mab

产品货号

AFRM9272

基因名称

POU5F1

蛋白名称

POU domain class 5 transcription factor 1

其他名称

POU5F1;OCT3;OCT4;OTF3;POU domain; class 5, transcription factor 1;Octamer-binding protein 3;Oct-3;Octamer-binding protein 4;Oct-4;Octamer-binding transcription factor 3;OTF-3

Gene ID

Human:5460    

SwissPro

Human:Q01860    

宿主种属

Rabbit

应用范围

WB;IHC;IF;IP;ELISA

稀释比例

IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

反应种属

Human; Mouse

克隆性

Monoclonal

克隆号

AFKL9272

特异性

endogenous

同种型

Rabbit IgG

保存液

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化方式

Protein A

保存条件

-20°C/1 year

背景资料

45kD

产品概述

This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One