产品名称

MiTF Rabbit mab

产品货号

AFRM9062

基因名称

MITF

蛋白名称

Microphthalmia-associated transcription factor

其他名称

MITF;BHLHE32;Microphthalmia-associated transcription factor;Class E basic helix-loop-helix protein 32;bHLHe32

Gene ID

Human:4286    

SwissPro

Human:O75030    

宿主种属

Rabbit

应用范围

WB;IHC;IF;IP;ELISA

稀释比例

IHC 1:200-500,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

反应种属

Human; Mouse; Rat;

克隆性

Monoclonal

克隆号

AFKL9062

特异性

endogenous

同种型

Rabbit IgG

保存液

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化方式

Protein A

保存条件

-20°C/1 year

背景资料

58kD

产品概述

This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding di