产品名称 | Rad21 Rabbit mab |
产品货号 | AFRM9075 |
基因名称 | RAD21 |
蛋白名称 | Double-strand-break repair protein rad21 homolog |
其他名称 | RAD21;HR21;KIAA0078;NXP1;Double-strand-break repair protein rad21 homolog;hHR21;Nuclear matrix protein 1;NXP-1;SCC1 homolog |
Gene ID | Human:5885     |
SwissPro | Human:O60216     |
宿主种属 | Rabbit |
应用范围 | WB;IHC;IF;IP;ELISA |
稀释比例 | IHC 1:200-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200 |
反应种属 | Human; Mouse; Rat; |
克隆性 | Monoclonal |
克隆号 | AFKL9075 |
特异性 | endogenous |
同种型 | Rabbit IgG |
保存液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
纯化方式 | Protein A |
保存条件 | -20°C/1 year |
背景资料 | 130kD |
产品概述 | The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided |