产品名称

CD105 Rabbit mab

产品货号

AFRM9089

基因名称

ENG END

蛋白名称

Endoglin (CD antigen CD105)

Gene ID

Human:2022    

SwissPro

Human:P17813    

宿主种属

Rabbit

应用范围

WB;IHC;IF;IP;ELISA

稀释比例

IHC 1:100-200,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

反应种属

Human;

克隆性

Monoclonal

克隆号

AFKL9089

特异性

endogenous

同种型

Rabbit IgG

保存液

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化方式

Protein A

保存条件

-20°C/1 year

背景资料

95kD

产品概述

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of c