产品名称

ALIX Rabbit mab

产品货号

AFRM9063

基因名称

PDCD6IP AIP1 ALIX KIAA1375

蛋白名称

Alix

其他名称

Programmed cell death 6-interacting protein (PDCD6-interacting protein;ALG-2-interacting protein 1;Hp95)

Gene ID

Human:10015    

SwissPro

Human:Q8WUM4    

宿主种属

Rabbit

应用范围

WB;IHC;IF;IP;ELISA

稀释比例

IHC 1:200-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

反应种属

Human; Mouse; Rat;

克隆性

Monoclonal

克隆号

AFKL9063

特异性

endogenous

同种型

Rabbit IgG

保存液

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化方式

Protein A

保存条件

-20°C/1 year

背景资料

96kD

产品概述

This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane